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Samples were heated at 195 C until solution appeared clear (approximately 2-3 hours), then cooled to room temperature and adjusted to 250 L with ddH 2 O

Experimental Cell Research 361 (2), 324332

In this regard, the ability of various phytochemicals to enhance sirtuin activity and restore dysregulated metabolic signaling further supports sirtuin modulation as a promising strategy for phytochemical-based therapeutic intervention in PD